Investigative ophthalmology & visual science۲۰۲۵۳ استنادنمایه شده در PubMed
Ruiheng Zhang, Chuyao Yu, Yitong Li, Jiaoyue Dong, Haotian Wu, Yuhang Yang, Xuhan Shi, Wenda Zhou, Hanqing Zhao, Bingyu Cai, Shanshan Wang, Li Dong, Lei Shao, Wei Li, Jost B Jonas, Wenbin Wei
چکیده
The mechanistic target of rapamycin complex 1 (mTORC1) signaling has been reported to regulate lens-induced myopia (LIM) in guinea pigs. To address the challenge of delivering lipophilic mTORC1 inhibitors to the posterior eye segment, we developed a novel topical ophthalmic formulation of…
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DOI: 10.1167/iovs.66.12.55