Investigative ophthalmology & visual science۲۰۲۵نمایه شده در PubMed
Erik A Souverein, Sanyukta Oak, Zachary Fouladian, Mark W Reid, G Esteban Fernandez, Andrew Salas, Jennifer G Aparicio, Aaron Nagiel, Ksenia Gnedeva
چکیده
To investigate whether Hippo pathway inhibition via a novel Lats kinase inhibitor (LKI) induces regeneration of retinal pigment epithelium (RPE). An in vitro scratch "injury" on confluent RPE monolayers was produced using the Woundmaker Tool. A 6×6 grid of laser spots was delivered to the central…
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DOI: 10.1167/iovs.66.6.69