Investigative ophthalmology & visual science۲۰۲۵۵ استنادنمایه شده در PubMed
Peter Kiraly, Joshua Klein, Immanuel P Seitz, Felix F Reichel, Tobias Peters, Taras Ardan, Jana Juhasova, Stefan Juhás, Zdenka Ellederova, Yaroslav Nemesh, Ruslan Nyshchuk, Nikolai Klymiuk, Kerstin Nagel-Wolfrum, Ashley R Winslow, Uwe Wolfrum, Jan Motlik, M Dominik Fischer
چکیده
This study aimed to evaluate early-phase safety of subretinal application of AAVanc80.CAG.USH1Ca1 (OT_USH_101) in wild-type (WT) pigs, examining the effects of a vehicle control, low dose, and high dose. Twelve WT pigs (24 eyes) were divided into three groups: four pigs each received bilateral…
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DOI: 10.1167/iovs.66.1.48