Dualistic Role of MITF in Uveal Melanoma: Defining Two Distinct Cellular Subpopulations With Prognostic and Therapeutic Implications.

چکیده

Microphthalmia-associated transcription factor (MITF) regulates melanocyte differentiation, proliferation, and survival, intersecting with oncogenic and tumor-suppressive pathways. However, its prognostic significance in uveal melanoma (UM) remains unexplored in large cohorts. This study examines…

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موضوعات مرتبط

• تومورهای چشم